It's Week 13, and the San Francisco 49ers are at 5-6 in the season. The team travels to Buffalo to take on the leaders of the ...

With no teams on a bye, Week 13 Fantasy football lineups are more stacked than previous weeks. Who you deploy as part of your ...

There are no fewer than 20 running backs who could finish the season as 1,000-yard rushers, with Saquon Barkley carrying the ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...

The San Francisco 49ers will travel to take on the Buffalo Bills in Week 13. Here’s the final injury report and start-sit advice for every skill player who has the potential to make a fantasy football ...

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

Running back Christian McCaffrey refuses to buy into the doom and gloom surrounding the San Francisco 49ers since two ...

Head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, DL Nick Bosa and others and discussed the team's ...

There’s a running back renaissance taking place in the NFL and Christian McCaffrey has yet to take part in it.

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night ...