The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

San Francisco 49ers quarterback Brock Purdy official game status revealed for Week 13 primetime matchup against the Buffalo ...

San Francisco 49ers quarterback Brock Purdy is expected to play Sunday night against the Buffalo Bills, according to ESPN's ...

The San Francisco 49ers are extremely banged up going into their Week 13 showdown with the Buffalo Bills. However, they will ...

The San Francisco 49ers have not looked dominant in 2024 like last season. However, they could bring in some new faces in ...

San Francisco 49ers quarterback Brock Purdy missed the team's loss to the Green Bay Packers in Week 12 with a shoulder injury ...

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available ...

A pair of Super Bowl hopefuls from each conference meet up on Sunday, Dec. 1 to close out the NFL schedule for the day with ...

The San Francisco 49ers suffered another crushing defeat Sunday night, falling 35-10 to the Buffalo Bills. The loss marked ...

San Francisco 49ers quarterback Brock Purdy is active for the team's Week 13 matchup versus the Buffalo Bills.

The ailing 49ers will have their starting quarterback under center Sunday. Brock Purdy, who missed the first start of his ...