The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local ...

We've seen this before in Buffalo -- a lake effect snowstorm dumps tons of snow on Highmark Stadium for a Bills game. That's ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

After U.S. travelers battled through harsh weekend weather to reach home following the Thanksgiving holiday, residents of the ...

Parts of the Great Lakes region saw new snow Monday and faced the prospect of even more this week after U.S. travelers ...

Snowplow crews are working around the clock to keep up with this weekend’s lake-effect snowfall, including a crew in Orchard ...

Allen scored a traditional rushing touchdown early in the fourth quarter, giving him three touchdowns on two plays in the ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Tonight the Buffalo Bills will proceed with playing the San Francisco 49ers at 8:20 p.m. Orchard Park already had 22.9 inches ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...