The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...

Buffalo Bills head coach Sean McDermott has ruled out tight end Dalton Kincaid for Sunday night's game against the San ...

The Bills’ defense has plenty of experience against 21 personnel because Miami runs it the second most of any team in the NFL ...

The Buffalo Bills (9-2) roll on in their 2024 regular season journey with a matchup at home against the San Francisco 49ers ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The San Francisco 49ers could have Brock Purdy back soon, as the quarterback was recently seen throwing passes in a video ...

Defeating the Bills on the road will be extremely difficult for the 49ers, but they do have a favorable matchup on defense.

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

The San Francisco 49ers announced they have signed OL Sebastian Gutierrez to the team's practice squad. In order to make room ...