It’s been a rough day – and a rough season - for 49ers fans. Many are depressed over a brutal loss Monday night in Buffalo ...

The 49ers just lost their second game in a row by at least 25 points for the first time since Jim Tomsula was the head coach.

Kyle Shanahan and the San Francisco 49ers are rallying around Trent Williams and Charvarius Ward after the NFL stars both ...

Williams’ wife, Sondra, announced on Instagram on Sunday, Dec. 1 that their son Trenton O'Brien Williams Jr. was stillborn on ...

San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

San Francisco 49ers star running back Christian McCaffrey is out for the rest of 2024 after suffering a significant knee ...

The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

The San Francisco 49ers suffered another disappointing loss on Sunday night as they took on the Buffalo Bills on the road in ...

The Los Angeles Rams' bitter rival suffered yet another devastating injury during their Week 13 road loss against the Buffalo ...

The San Francisco 49ers were hit by another family tragedy with the announcement that star left tackle Trent Williams’ wife ...

The San Francisco 49ers were handed a major loss under the bright lights of primetime football at Highmark Stadium as the ...