The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

Former Wisconsin running back Isaac Guerendo scored the second touchdown of his young NFL career in the San Francisco 49ers’ ...

The Great Lakes region is seeing new snow and faces the prospect of even more this week after U.S. travelers battled harsh weather to get home after Thanksgiving ...

The National Weather Service said that snow was expected to fall in the region into Monday morning and again Wednesday and ...

Two sides stuck on losing streaks meet at the Levi's Stadium in Game Week 14.  The Buffalo Bills comfortably beat the 49ers ...

The Buffalo Bills confirmed their fifth AFC top-spot in a row with a victory over the San Franciso 49ers and head to LA in ...

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Tonight the Buffalo Bills will proceed with playing the San Francisco 49ers at 8:20 p.m. Orchard Park already had 22.9 inches ...

Following a brutal 38-10 loss to the Green Bay Packers last week, things didn't get any easier for the San Francisco 49ers ...

Josh Allen became the first quarterback since 1970 to score a rushing touchdown, pass for a touchdown and have a scoring ...

If you had on your bingo card Buffalo Bills coach Sean McDermott laying down on the snow covered turf at Highmark Stadium doing snow angels next to quarterback Josh Allen late Sunday night, well bolly ...

The Pittsburgh Steelers outlasted the Cincinnati Bengals in a 44-38 win on the road. Quarterback Russell Wilson had a vintage ...