After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local ...

Leading the way once again was the Bills’ quarterback, who was responsible for three of his team’s five touchdowns. ...

How much snow is on the ground at Highmark Stadium ahead of the Buffalo Bills' Week 13 clash with the San Francisco 49ers?

Sunday's Week 13 of the 2024 NFL season concludes with a massive clash between the Bills and 49ers. Here's updates of ...

Orchard Park, New York, where the Bills’ Highmark Stadium is located, saw 23 inches of snow. But the Bills have had staffers ...