San Francisco fumbled the ball three times and lost all three. Brock Purdy dropped back to pass 20 times for 86 net yards.

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

A picturesque setting of snow was the perfect backdrop for a Buffalo Bills team that has now won its fifth straight AFC East ...

After the game, Bills quarterback Josh Allen and coach Sean McDermott soaked in the winter weather while celebrating the team ...

Lake-effect snow has been hitting Buffalo throughout the holiday weekend with is expected to continue off and on through ...

A Buffalo Bills fan seemingly tried to use the snowy weather to their advantage on Sunday night as they appeared to toss a ...

Somehow Week 13 was worse than for the San Francisco 49ers than Week 12. The 49ers fell behind 21-3 at halftime and had a ...