Following new injury reports, updated simulations reveal the best bet for 49ers vs. Bills on Sunday Night Football. Injury ...

Dive into the San Francisco 49ers vs. Buffalo Bills showdown with a look at odds, predictions, and the best betting options.

San Francisco 49ers cornerback Charvarius Ward announced his daughter's death on Oct. 29, and he left the team to be with ...

ORCHARD PARK, N.Y. (AP) — Josh Allen’s latest kneel-down had nothing to do with football.

Forecasters warn 4 to 6 feet of blowing and drifting snow could fall in Watertown and other areas east of Lake Ontario ...

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

T he Buffalo Bills enjoyed their BYE week prior to facing the San Francisco 49ers this Sunday, and superstar quarterback Josh ...

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

Brock Purdy speaks with reporters ahead of San Francisco's Week 13 matchup against the Buffalo Bills on Sunday night.49ers QB ...