One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The Buffalo Bills (9-2) roll on in their 2024 regular season journey with a matchup at home against the San Francisco 49ers ...

Buffalo Bills head coach Sean McDermott has ruled out tight end Dalton Kincaid for Sunday night's game against the San ...

Buffalo Bills rookie wide receiver Keon Coleman has been designated as questionable for his team's Week 13 matchup with the ...

Defeating the Bills on the road will be extremely difficult for the 49ers, but they do have a favorable matchup on defense.

Buffalo Bills linebacker Matt Milano hasn't played in 2024, but he could make his debut on Sunday. Carson Field has the ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

Break out the shovels, Bills Mafia. Meteorologists are anticipating upwards of a foot of snow to fall atop Orchard Park prior ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The Buffalo Bills (9-2) bring a six-game winning streak into a matchup with the San Francisco 49ers (5-6) on Sunday, December ...

Buffalo Bills coach Sean McDermott ruled out Dalton Kincaid from playing against San Francisco on Sunday night, while holding ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...