The Buffalo Bills (9-2) roll on in their 2024 regular season journey with a matchup at home against the San Francisco 49ers ...

Buffalo Bills head coach Sean McDermott has ruled out tight end Dalton Kincaid for Sunday night's game against the San ...

Buffalo Bills rookie wide receiver Keon Coleman has been designated as questionable for his team's Week 13 matchup with the ...

Defeating the Bills on the road will be extremely difficult for the 49ers, but they do have a favorable matchup on defense.

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

The San Francisco 49ers could have Brock Purdy back soon, as the quarterback was recently seen throwing passes in a video ...

Heavy, lake-effect snow will fall on Buffalo this weekend as the 49ers arrive to face the Bills on Sunday night in the suburb ...