The San Francisco 49ers could have Brock Purdy back soon, as the quarterback was recently seen throwing passes in a video after being limited in practice just a few days ago due to injury concerns. Brock Purdy could return to the starting role for the San Francisco 49ers in Week 13 against the Buffalo Bills on the road.

The San Francisco 49ers, despite careening toward the abyss of NFL mediocrity, still have a path to the postseason as they enter their Week 13 showdown against the Buffalo Bills. Yet, thanks to the rest of the NFC West's tussle with the .

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth Lombardi Trophy. The Niners have mad

The San Francisco 49ers announced they have signed OL Sebastian Gutierrez to the team's practice squad. In order to make room on the practice squad, the team released OL Cameron Erving. Gutierrez (6-6, 310) originally entered the NFL after signing with the ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4. Warner suffered the injury

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio, the Bills Radio Network has stations all across the state. Chris Brown has the play-by-play, Eric Wood is the analyst, and Sal Capaccio is the sideline reporter. The network includes:

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

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Buffalo Bills head coach Sean McDermott has ruled out tight end Dalton Kincaid for Sunday night's game against the San Francisco 49ers.

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.